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Objective:To observe the clinical effect and safety of diammonium glycyrrhetate(DG) in the treatment of psoriasis vulgaris. Methods:48 patients were randornly divided into two groups treated group(28 cases)and controlled group(20 cases). Both were given DG or common drugs, respectively. Results:Effective rate was 67.9%(19/28), mean effect-begining time was 17.42±2.36 days in the treated group, they were significantly increased in comparison with controlled group(Effective rate was 30.0%, mean effect-begining time was 25.65±3.54 days). Any side effect was not occurred in treated group. Conclusion:DG is effective and safe in the treatment patients with psoriasis vulgaris.
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Objective: To explore the infection of mycoplasma in the venereal diseases and information about their drug susceptibility. Methods: Materials from the 12 528 patients were cultivated and drug susceptibility made testing was made using the mycoplasma IST Kit. Results: The results showed that 9433 of 12 528 (75.3%)were infected by mycoplasma, Uu infective rate 58.3 %(7 305 cases)was found significantly higher than Mh infective rate 3.0%(379 cases)and mixed infection of both Uu and Mh was 14.0%(1 749 cases,)P＜0.01. The no susceptible conditions were in turn that ofloxacine(50.5%), Erythromycine(41.9%), tetracycline(14.6%), doxycycline(4.7%), josamycine(2.9%), and pristinamycine(2.0%) respectively. Conclusions:The results suggested that non-gonococcal genitourinary tract infection was firstly ureaplasma urealyticum, concentracted infection was at age 21-40 years. no susceptible stat of mycoplasma infection to drug was serious, so that susceptibility testing of mycoplasma had a important significance to clinical drug treatment.
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The therapeutic effect and mechanism of moxibustion in the treatment of Herpes Zoster were studied. It was found that the level of T lymphocyte subsets of the patients with Herpes Zoster was within the normal range before treatment, but slightly lower than in the health group. Th cells and NK cells were significantly decreased in the patients with Herpes Zoster as compared with those in the health group (P＜0. 05),suggesting the cellular immunity of the patients with Herpes Zoster was decreased. After treatment with moxibustion, the level of all the T lymphocyte subsets was increased, close to the normal. Among them the levels of Th cells and NK cells were significantly different from those before the treatment (P＜0. 05). The disappearance of exanthema and relief of neuralgia in the patients was also quicker than in the controls (P＜0. 01). It was indicated that moxibustion had a good effect in the treatment of Herpes Zoster, which was contributed to the enhancement of the body antiviral ability by the improvement of immunity, especially the cellular immunity.
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Objective To investigate the expression of fragile histid ine triad (FHIT)gene and its relationship with the proliferation and apoptosis of tumor cells in cutaneous malignant melanoma (CMM).Methods The expression o f FHIT gene and PCNA were detected by streptavidin peroxidase method with skin s pecimens taken from 57 primary cutaneous melanoma and 20 normal controls.Apopto sis of tumor cells was detected by terminal deoxynuclneotidyl transferase mediat ed dUTP nick end labeling (TUNEL).Results The expression level of FHIT protei n was significantly lower in CMM than that in the normal skin tissue (P